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En el instante 23 de junio de 2026, 16:06:49 UTC,
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Modificado el valor del campo
spatial_coverage
a[{'bbox': '{"type": "Polygon", "coordinates": [[[-2.34, 37.38], [-0.69, 37.38], [-0.69, 38.76], [-2.34, 38.76], [-2.34, 37.38]]]}', 'centroid': '{"type": "Point", "coordinates": [-1.515, 38.07]}', 'text': 'Región de Murcia', 'uri': 'http://datos.gob.es/recurso/sector-publico/territorio/Autonomia/Region-Murcia'}]
en Toxicity characterization of surface sediments from a Mediterranean coastal lagoon
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| 95 | "notes": "The occurrence of bioactive compounds and | 95 | "notes": "The occurrence of bioactive compounds and | ||
| 96 | contaminant-associated effects was assessed by means of in vivo and in | 96 | contaminant-associated effects was assessed by means of in vivo and in | ||
| 97 | vitro assays using different extractable fractions of surface | 97 | vitro assays using different extractable fractions of surface | ||
| 98 | sediments from a contaminated coastal lagoon (Mar Menor, SE Spain). | 98 | sediments from a contaminated coastal lagoon (Mar Menor, SE Spain). | ||
| 99 | Sediment elutriates and clean seawater, previously exposed to whole | 99 | Sediment elutriates and clean seawater, previously exposed to whole | ||
| 100 | sediment, were used for assessing the in vivo toxicity on embryo | 100 | sediment, were used for assessing the in vivo toxicity on embryo | ||
| 101 | development of the sea urchin Paracentrotus lividus. Agonist and | 101 | development of the sea urchin Paracentrotus lividus. Agonist and | ||
| 102 | antagonist activities relating to estrogen and androgen receptors and | 102 | antagonist activities relating to estrogen and androgen receptors and | ||
| 103 | agonist activities on aryl hydrocarbon receptor (expressed as | 103 | agonist activities on aryl hydrocarbon receptor (expressed as | ||
| 104 | ethoxyresorufin-O-deethylase (EROD) activities) were investigated in | 104 | ethoxyresorufin-O-deethylase (EROD) activities) were investigated in | ||
| 105 | sediment extracts by using HER-Luc, AR-EcoScreenTM and fibroblast-like | 105 | sediment extracts by using HER-Luc, AR-EcoScreenTM and fibroblast-like | ||
| 106 | RTG-2 cell lines. Embryotoxicity effects were greater for sediment | 106 | RTG-2 cell lines. Embryotoxicity effects were greater for sediment | ||
| 107 | elutriates than those incubated in sediment-water interphase, implying | 107 | elutriates than those incubated in sediment-water interphase, implying | ||
| 108 | that diffusion of bioactive chemicals can occur from sediments to sea | 108 | that diffusion of bioactive chemicals can occur from sediments to sea | ||
| 109 | water column, favoured by sediment disturbance events. In vitro | 109 | water column, favoured by sediment disturbance events. In vitro | ||
| 110 | results show the occurrence in extracts of compounds with estrogen | 110 | results show the occurrence in extracts of compounds with estrogen | ||
| 111 | antagonism, androgen antagonism and dioxin-like activities. | 111 | antagonism, androgen antagonism and dioxin-like activities. | ||
| 112 | Multidimensional scaling analysis classified the sampling sites into | 112 | Multidimensional scaling analysis classified the sampling sites into | ||
| 113 | four sub-clusters according to their chemical-physical and biological | 113 | four sub-clusters according to their chemical-physical and biological | ||
| 114 | similarities, relating in vitro bioactivity with the total organic | 114 | similarities, relating in vitro bioactivity with the total organic | ||
| 115 | carbon and known organic chemical load, with particular reference to | 115 | carbon and known organic chemical load, with particular reference to | ||
| 116 | total sum of PAHs, PCB 180, p,p-DDE and terbuthylazine. Overall, | 116 | total sum of PAHs, PCB 180, p,p-DDE and terbuthylazine. Overall, | ||
| 117 | results pointed to the presence of unknown or unanalyzed | 117 | results pointed to the presence of unknown or unanalyzed | ||
| 118 | biologically-active compounds in the sediments, mostly associated with | 118 | biologically-active compounds in the sediments, mostly associated with | ||
| 119 | the extracted polar fraction of the Mar Menor lagoon sediments. Our | 119 | the extracted polar fraction of the Mar Menor lagoon sediments. Our | ||
| 120 | findings provide relevant information to be considered for the | 120 | findings provide relevant information to be considered for the | ||
| 121 | environmental management of contaminated coastal lagoons. (C) 2020 | 121 | environmental management of contaminated coastal lagoons. (C) 2020 | ||
| 122 | Elsevier Ltd. All rights reserved.", | 122 | Elsevier Ltd. All rights reserved.", | ||
| 123 | "notes_translated": { | 123 | "notes_translated": { | ||
| 124 | "es": "The occurrence of bioactive compounds and | 124 | "es": "The occurrence of bioactive compounds and | ||
| 125 | contaminant-associated effects was assessed by means of in vivo and in | 125 | contaminant-associated effects was assessed by means of in vivo and in | ||
| 126 | vitro assays using different extractable fractions of surface | 126 | vitro assays using different extractable fractions of surface | ||
| 127 | sediments from a contaminated coastal lagoon (Mar Menor, SE Spain). | 127 | sediments from a contaminated coastal lagoon (Mar Menor, SE Spain). | ||
| 128 | Sediment elutriates and clean seawater, previously exposed to whole | 128 | Sediment elutriates and clean seawater, previously exposed to whole | ||
| 129 | sediment, were used for assessing the in vivo toxicity on embryo | 129 | sediment, were used for assessing the in vivo toxicity on embryo | ||
| 130 | development of the sea urchin Paracentrotus lividus. Agonist and | 130 | development of the sea urchin Paracentrotus lividus. Agonist and | ||
| 131 | antagonist activities relating to estrogen and androgen receptors and | 131 | antagonist activities relating to estrogen and androgen receptors and | ||
| 132 | agonist activities on aryl hydrocarbon receptor (expressed as | 132 | agonist activities on aryl hydrocarbon receptor (expressed as | ||
| 133 | ethoxyresorufin-O-deethylase (EROD) activities) were investigated in | 133 | ethoxyresorufin-O-deethylase (EROD) activities) were investigated in | ||
| 134 | sediment extracts by using HER-Luc, AR-EcoScreenTM and fibroblast-like | 134 | sediment extracts by using HER-Luc, AR-EcoScreenTM and fibroblast-like | ||
| 135 | RTG-2 cell lines. Embryotoxicity effects were greater for sediment | 135 | RTG-2 cell lines. Embryotoxicity effects were greater for sediment | ||
| 136 | elutriates than those incubated in sediment-water interphase, implying | 136 | elutriates than those incubated in sediment-water interphase, implying | ||
| 137 | that diffusion of bioactive chemicals can occur from sediments to sea | 137 | that diffusion of bioactive chemicals can occur from sediments to sea | ||
| 138 | water column, favoured by sediment disturbance events. In vitro | 138 | water column, favoured by sediment disturbance events. In vitro | ||
| 139 | results show the occurrence in extracts of compounds with estrogen | 139 | results show the occurrence in extracts of compounds with estrogen | ||
| 140 | antagonism, androgen antagonism and dioxin-like activities. | 140 | antagonism, androgen antagonism and dioxin-like activities. | ||
| 141 | Multidimensional scaling analysis classified the sampling sites into | 141 | Multidimensional scaling analysis classified the sampling sites into | ||
| 142 | four sub-clusters according to their chemical-physical and biological | 142 | four sub-clusters according to their chemical-physical and biological | ||
| 143 | similarities, relating in vitro bioactivity with the total organic | 143 | similarities, relating in vitro bioactivity with the total organic | ||
| 144 | carbon and known organic chemical load, with particular reference to | 144 | carbon and known organic chemical load, with particular reference to | ||
| 145 | total sum of PAHs, PCB 180, p,p-DDE and terbuthylazine. Overall, | 145 | total sum of PAHs, PCB 180, p,p-DDE and terbuthylazine. Overall, | ||
| 146 | results pointed to the presence of unknown or unanalyzed | 146 | results pointed to the presence of unknown or unanalyzed | ||
| 147 | biologically-active compounds in the sediments, mostly associated with | 147 | biologically-active compounds in the sediments, mostly associated with | ||
| 148 | the extracted polar fraction of the Mar Menor lagoon sediments. Our | 148 | the extracted polar fraction of the Mar Menor lagoon sediments. Our | ||
| 149 | findings provide relevant information to be considered for the | 149 | findings provide relevant information to be considered for the | ||
| 150 | environmental management of contaminated coastal lagoons. (C) 2020 | 150 | environmental management of contaminated coastal lagoons. (C) 2020 | ||
| 151 | Elsevier Ltd. All rights reserved." | 151 | Elsevier Ltd. All rights reserved." | ||
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