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  "notes": "The bioaccumulation of 20 pharmaceuticals in cockle 
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  "notes": "The bioaccumulation of 20 pharmaceuticals in cockle 
            
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(Cerastodema glaucum), noble pen shell (Pinna nobilis), sea snail 
105
(Cerastodema glaucum), noble pen shell (Pinna nobilis), sea snail 
            
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(Murex trunculus), golden grey mullet (Liza aurata) and black goby 
106
(Murex trunculus), golden grey mullet (Liza aurata) and black goby 
            
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(Gobius niger) was evaluated, considering their distribution 
107
(Gobius niger) was evaluated, considering their distribution 
            
98
throughout the Mar Menor lagoon and their variations in spring and 
108
throughout the Mar Menor lagoon and their variations in spring and 
            
99
autumn 2010. The analytical procedure was adapted for the different 
109
autumn 2010. The analytical procedure was adapted for the different 
            
100
matrices as being sensitive and reproducible. Eighteen out of the 20 
110
matrices as being sensitive and reproducible. Eighteen out of the 20 
            
101
compounds analysed were found at low ng g(-1) in these species 
111
compounds analysed were found at low ng g(-1) in these species 
            
102
throughout the lagoon. Hydrochlorothiazide and carbamazepine were 
112
throughout the lagoon. Hydrochlorothiazide and carbamazepine were 
            
103
detected in all species considered. The bioaccumulation of 
113
detected in all species considered. The bioaccumulation of 
            
104
pharmaceuticals was heterogeneous in the lagoon, with a higher number 
114
pharmaceuticals was heterogeneous in the lagoon, with a higher number 
            
105
of pharmaceuticals being detected in fish (18) than in wild molluscs 
115
of pharmaceuticals being detected in fish (18) than in wild molluscs 
            
106
(8), particularly in golden grey mullet muscle (16). B-blockers and 
116
(8), particularly in golden grey mullet muscle (16). B-blockers and 
            
107
psychiatric drugs were preferentially bioccumulated in fish and 
117
psychiatric drugs were preferentially bioccumulated in fish and 
            
108
hydrochlorothiazide was also confirmed in caged clams. The higher 
118
hydrochlorothiazide was also confirmed in caged clams. The higher 
            
109
detection frequency and concentrations found in golden grey mullet 
119
detection frequency and concentrations found in golden grey mullet 
            
110
suggested that mugilids could be used as an indicator of contamination 
120
suggested that mugilids could be used as an indicator of contamination 
            
111
by pharmaceuticals in coastal areas. To the best of our knowledge, 
121
by pharmaceuticals in coastal areas. To the best of our knowledge, 
            
112
this is the first study that shows data about hydrochlorothiazide, 
122
this is the first study that shows data about hydrochlorothiazide, 
            
113
levamisole and codeine in wild marine biota. (C) 2016 Elsevier Inc. 
123
levamisole and codeine in wild marine biota. (C) 2016 Elsevier Inc. 
            
114
All rights reserved.",
124
All rights reserved.",
            
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  "notes_translated": {
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    "es": "The bioaccumulation of 20 pharmaceuticals in cockle 
126
    "es": "The bioaccumulation of 20 pharmaceuticals in cockle 
            
117
(Cerastodema glaucum), noble pen shell (Pinna nobilis), sea snail 
127
(Cerastodema glaucum), noble pen shell (Pinna nobilis), sea snail 
            
118
(Murex trunculus), golden grey mullet (Liza aurata) and black goby 
128
(Murex trunculus), golden grey mullet (Liza aurata) and black goby 
            
119
(Gobius niger) was evaluated, considering their distribution 
129
(Gobius niger) was evaluated, considering their distribution 
            
120
throughout the Mar Menor lagoon and their variations in spring and 
130
throughout the Mar Menor lagoon and their variations in spring and 
            
121
autumn 2010. The analytical procedure was adapted for the different 
131
autumn 2010. The analytical procedure was adapted for the different 
            
122
matrices as being sensitive and reproducible. Eighteen out of the 20 
132
matrices as being sensitive and reproducible. Eighteen out of the 20 
            
123
compounds analysed were found at low ng g(-1) in these species 
133
compounds analysed were found at low ng g(-1) in these species 
            
124
throughout the lagoon. Hydrochlorothiazide and carbamazepine were 
134
throughout the lagoon. Hydrochlorothiazide and carbamazepine were 
            
125
detected in all species considered. The bioaccumulation of 
135
detected in all species considered. The bioaccumulation of 
            
126
pharmaceuticals was heterogeneous in the lagoon, with a higher number 
136
pharmaceuticals was heterogeneous in the lagoon, with a higher number 
            
127
of pharmaceuticals being detected in fish (18) than in wild molluscs 
137
of pharmaceuticals being detected in fish (18) than in wild molluscs 
            
128
(8), particularly in golden grey mullet muscle (16). B-blockers and 
138
(8), particularly in golden grey mullet muscle (16). B-blockers and 
            
129
psychiatric drugs were preferentially bioccumulated in fish and 
139
psychiatric drugs were preferentially bioccumulated in fish and 
            
130
hydrochlorothiazide was also confirmed in caged clams. The higher 
140
hydrochlorothiazide was also confirmed in caged clams. The higher 
            
131
detection frequency and concentrations found in golden grey mullet 
141
detection frequency and concentrations found in golden grey mullet 
            
132
suggested that mugilids could be used as an indicator of contamination 
142
suggested that mugilids could be used as an indicator of contamination 
            
133
by pharmaceuticals in coastal areas. To the best of our knowledge, 
143
by pharmaceuticals in coastal areas. To the best of our knowledge, 
            
134
this is the first study that shows data about hydrochlorothiazide, 
144
this is the first study that shows data about hydrochlorothiazide, 
            
135
levamisole and codeine in wild marine biota. (C) 2016 Elsevier Inc. 
145
levamisole and codeine in wild marine biota. (C) 2016 Elsevier Inc. 
            
136
All rights reserved."
146
All rights reserved."
            
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