The Mar Menor is a hypersaline coastal lagoon with salinity values ranging from 41.9 to 45.5. The systemis subjected to a high anthropic pressure that causes an intense eutrophication process, followed by a recovery of the macrophyte meadows. This study focuses on the distribution of the main greenhouse gases (CO2, CH4 and N2O) and was carried out in the extreme seasonal conditions of winter and summer during the year 2018. Sediment-water-atmosphere exchanges and biochemical processes in the water column appeared to be the main factors to explain the variability of these gases.Dissolved Inorganic Carbon (DIC), CH4 and N2O benthic fluxes values obtained in this study, were of 91 +/- 29 mmol m(-2) d(-1), 3.9 +/- 1.9 mu mol m(-2) d(-1) and -0.65 mu mol m(-2) d(-1), respectively, along with an important seasonal variation observed, with an increase of DIC and CH4 benthic fluxes during the summer season. Mean values of partial pressure of CO2 (pCO(2)) in surfacewaterwere of 579 mu atm in winter and 464 mu atmin summer, therefore we can establish that the Mar Menor acts as a source of this gas emitting 3.3 +/- 3.0 mmol CO2 m(-2) d(-1) to the atmosphere. In spite of this, the Mar Menor has a strong autotrophic behaviour partly due to the recovery of the macrophyte meadows, presenting an estimated NEP of 101 mmol m(-2) d(-1). Regarding to CH4, the mean fluxes to the atmosphere were of 8.0 +/- 5.8 mu mol m(-2) d(-1) and there was evidence of CH4 production in the water column that increased in summer. Last of all, in the case of N2O the system acts as a sink with values of -0.65 +/- 0.5 mu mol m(-2) d(-1), presenting an intake of N2O that is usually detected in pristine systems. (C) 2021 Elsevier B.V. All rights reserved.